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Lack of Eosinophil Peroxidase or Major Basic Protein Impairs Defense against Murine Filarial Infection

Eosinophils are a hallmark of allergic diseases and helminth infection, yet direct evidence for killing of helminth parasites by their toxic granule products exists only in vitro. We investigated the in vivo roles of the eosinophil granule proteins eosinophil peroxidase (EPO) and major basic protein...

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Autors principals: Specht, Sabine, Saeftel, Michael, Arndt, Manuela, Endl, Elmar, Dubben, Bettina, Lee, Nancy A., Lee, James J., Hoerauf, Achim
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594830/
https://ncbi.nlm.nih.gov/pubmed/16926417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00329-06
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