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Hernia fibroblasts lack β-estradiol induced alterations of collagen gene expression

BACKGROUND: Estrogens are reported to increase type I and type III collagen deposition and to regulate Metalloproteinase 2 (MMP-2) expression. These proteins are reported to be dysregulated in incisional hernia formation resulting in a significantly decreased type I to III ratio. We aimed to evaluat...

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Autors principals: Jansen, Petra Lynen, Rosch, Raphael, Rezvani, Melanie, Mertens, Peter R, Junge, Karsten, Jansen, Marc, Klinge, Uwe
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594569/
https://ncbi.nlm.nih.gov/pubmed/17010202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-7-36
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