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Insulin-like growth factor 1 is required for G(2) progression in the estradiol-induced mitotic cycle

Insulin-like growth factor 1 (IGF1) has been proposed as a “G(1)-progression factor” and as a mediator of estradiol’s (E2) mitogenic effects on the uterus. To test these hypotheses, we compared E2’s mitogenic effects on the uteri of Igf1-targeted gene deletion (null) and wild-type littermate mice. T...

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Detalhes bibliográficos
Main Authors: Adesanya, O. O., Zhou, J., Samathanam, C., Powell-Braxton, L., Bondy, C. A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15934/
https://ncbi.nlm.nih.gov/pubmed/10077676
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