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Locus-Wide Chromatin Remodeling and Enhanced Androgen Receptor-Mediated Transcription in Recurrent Prostate Tumor Cells

Prostate cancers (PCas) become resistant to hormone withdrawal through increased androgen receptor (AR) signaling. Here we show increased AR-mediated transcription efficiency in PCa cells that have acquired the ability to grow in low concentrations of androgen. Compared to androgen-dependent PCa cel...

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Detalhes bibliográficos
Main Authors: Jia, Li, Shen, Howard C., Wantroba, Marcus, Khalid, Omar, Liang, Gangning, Wang, Qingcai, Gentzschein, Elisabet, Pinski, Jacek K., Stanczyk, Frank Z., Jones, Peter A., Coetzee, Gerhard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592894/
https://ncbi.nlm.nih.gov/pubmed/16980632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00581-06
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