The ADAP/SKAP55 Signaling Module Regulates T-Cell Receptor-Mediated Integrin Activation through Plasma Membrane Targeting of Rap1

Adhesion of T cells after stimulation of the T-cell receptor (TCR) is mediated via signaling processes that have collectively been termed inside-out signaling. The molecular basis for inside-out signaling is not yet completely understood. Here, we show that a signaling module comprising the cytosoli...

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Auteurs principaux: Kliche, Stefanie, Breitling, Dennis, Togni, Mauro, Pusch, Rico, Heuer, Katja, Wang, Xiaoqian, Freund, Christian, Kasirer-Friede, Ana, Menasche, Gael, Koretzky, Gary A., Schraven, Burkhart
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592884/
https://ncbi.nlm.nih.gov/pubmed/16980616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00331-06
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