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Prostate-Specific Membrane Antigen Regulates Angiogenesis by Modulating Integrin Signal Transduction

The transmembrane peptidase prostate-specific membrane antigen (PSMA) is universally upregulated in the vasculature of solid tumors, but its functional role in tumor angiogenesis has not been investigated. Here we show that angiogenesis is severely impaired in PSMA-null animals and that this angioge...

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Main Authors: Conway, Rebecca E., Petrovic, Nenad, Li, Zhong, Heston, Warren, Wu, Dianqing, Shapiro, Linda H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592718/
https://ncbi.nlm.nih.gov/pubmed/16809768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00084-06
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