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Prostate-Specific Membrane Antigen Regulates Angiogenesis by Modulating Integrin Signal Transduction
The transmembrane peptidase prostate-specific membrane antigen (PSMA) is universally upregulated in the vasculature of solid tumors, but its functional role in tumor angiogenesis has not been investigated. Here we show that angiogenesis is severely impaired in PSMA-null animals and that this angioge...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1592718/ https://ncbi.nlm.nih.gov/pubmed/16809768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00084-06 |
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