Brain-derived proteins in the CSF, do they correlate with brain pathology in CJD?

BACKGROUND: Brain derived proteins such as 14-3-3, neuron-specific enolase (NSE), S 100b, tau, phosphorylated tau and Aβ(1–42 )were found to be altered in the cerebrospinal fluid (CSF) in Creutzfeldt-Jakob disease (CJD) patients. The pathogenic mechanisms leading to these abnormalities are not known...

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Auteurs principaux: Boesenberg-Grosse, Constanze, Schulz-Schaeffer, Walter J, Bodemer, Monika, Ciesielczyk, Barbara, Meissner, Bettina, Krasnianski, Anna, Bartl, Mario, Heinemann, Uta, Varges, Daniela, Eigenbrod, Sabina, Kretzschmar, Hans A, Green, Alison, Zerr, Inga
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2006
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592107/
https://ncbi.nlm.nih.gov/pubmed/16989662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2377-6-35
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