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Spatial and temporal regulation of gap junction connexin43 in vascular endothelial cells exposed to controlled disturbed flows in vitro

Hemodynamic regulation of the endothelial gap junction protein connexin43 (Cx43) was studied in a model of controlled disturbed flows in vitro. Cx43 mRNA, protein expression, and intercellular communication were mapped to spatial variations in fluid forces. Hemodynamic features of atherosclerotic le...

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Detalhes bibliográficos
Main Authors: DePaola, Natacha, Davies, Peter F., Pritchard, William F., Florez, Lucio, Harbeck, Nadeene, Polacek, Denise C.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15911/
https://ncbi.nlm.nih.gov/pubmed/10077653
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