Enhancement of fluid filtration across tumor vessels: Implication for delivery of macromolecules

Cancer therapies using genes and other macromolecules might realize their full clinical potential if they could be delivered to tumor tissue in optimal quantities. Unfortunately, the compromised circulation within tumors poses a formidable resistance to adequate and uniform penetration of these agen...

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Bibliographic Details
Main Authors: Netti, Paolo A., Hamberg, Leena M., Babich, John W., Kierstead, Diane, Graham, Wendy, Hunter, George J., Wolf, Gerald L., Fischman, Alan, Boucher, Yves, Jain, Rakesh K.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC15908/
https://ncbi.nlm.nih.gov/pubmed/10077650
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