Enhancement of fluid filtration across tumor vessels: Implication for delivery of macromolecules

Cancer therapies using genes and other macromolecules might realize their full clinical potential if they could be delivered to tumor tissue in optimal quantities. Unfortunately, the compromised circulation within tumors poses a formidable resistance to adequate and uniform penetration of these agen...

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Main Authors: Netti, Paolo A., Hamberg, Leena M., Babich, John W., Kierstead, Diane, Graham, Wendy, Hunter, George J., Wolf, Gerald L., Fischman, Alan, Boucher, Yves, Jain, Rakesh K.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC15908/
https://ncbi.nlm.nih.gov/pubmed/10077650
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