In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells

A rare set of hematopoietic stem cells (HSC) must undergo a massive expansion to produce mature blood cells. The phenotypic isolation of HSC from mice offers the opportunity to determine directly their proliferation kinetics. We analyzed the proliferation and cell cycle kinetics of long-term self-re...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Cheshier, Samuel H., Morrison, Sean J., Liao, Xinsheng, Weissman, Irving L.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1999
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15905/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10077647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.6.3120
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