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Random mutagenesis in Corynebacterium glutamicum ATCC 13032 using an IS6100-based transposon vector identified the last unknown gene in the histidine biosynthesis pathway

BACKGROUND: Corynebacterium glutamicum, a Gram-positive bacterium of the class Actinobacteria, is an industrially relevant producer of amino acids. Several methods for the targeted genetic manipulation of this organism and rational strain improvement have been developed. An efficient transposon muta...

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Detalhes bibliográficos
Main Authors: Mormann, Sascha, Lömker, Alexander, Rückert, Christian, Gaigalat, Lars, Tauch, Andreas, Pühler, Alfred, Kalinowski, Jörn
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1590026/
https://ncbi.nlm.nih.gov/pubmed/16901339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-7-205
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