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Smads orchestrate specific histone modifications and chromatin remodeling to activate transcription
Smads are intracellular transducers for TGF-β superfamily ligands, but little is known about the mechanism by which complexes of receptor-phosphorylated Smad2 and Smad4 regulate transcription. Using an in vitro transcription system, we have discovered that, unlike most transcription factors that are...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2006
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1589990/ https://ncbi.nlm.nih.gov/pubmed/16990801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601332 |
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