Metabolic regulation of sodium–calcium exchange by intracellular acyl CoAs

The sodium–calcium exchanger (NCX) is a critical mediator of calcium homeostasis. In the heart, NCX1 predominantly operates in forward mode to extrude Ca(2+); however, reverse-mode NCX1 activity during ischemia/reperfusion (IR) contributes to Ca(2+) loading and electrical and contractile dysfunction...

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Detalhes bibliográficos
Main Authors: Riedel, Michael J, Baczkó, István, Searle, Gavin J, Webster, Nicola, Fercho, Matthew, Jones, Lynn, Lang, Jessica, Lytton, Jonathan, Dyck, Jason R B, Light, Peter E
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1589979/
https://ncbi.nlm.nih.gov/pubmed/16977318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601321
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