Epidermal growth factor system regulates mucin production in airways

Goblet-cell hyperplasia is a critical pathological feature in hypersecretory diseases of airways. However, the underlying mechanisms are unknown, and no effective therapy exists. Here we show that stimulation of epidermal growth factor receptors (EGF-R) by its ligands, EGF and transforming growth fa...

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Main Authors: Takeyama, Kiyoshi, Dabbagh, Karim, Lee, Heung-Man, Agustí, Carlos, Lausier, James A., Ueki, Iris F., Grattan, Kathleen M., Nadel, Jay A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences 1999
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC15898/
https://ncbi.nlm.nih.gov/pubmed/10077640
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