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Cyclophilin C-associated protein: A normal secreted glycoprotein that down-modulates endotoxin and proinflammatory responses in vivo

Mouse cyclophilin C-associated protein (CyCAP) is a member of the scavenger-receptor cysteine-rich domain superfamily and is 69% identical to the human Mac-2 binding protein. Here, we show that CyCAP is a widely expressed secreted glycoprotein that modulates the host response to endotoxin. Gene-targ...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Trahey, Meg, Weissman, Irving L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15885/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10077627/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.6.3006
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