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Intact TRL 9 and type I interferon signaling pathways are required to augment HSV-1 induced corneal CXCL9 and CXCL10

Herpes simplex virus type 1 ocular infection elicits a potent inflammatory response including the production of the chemokines, CXCL9 and CXCL10, in mice. Since HSV-1 nucleic acid is recognized by pattern receptors including toll-like receptor (TLR) 9, we tested the hypothesis that TLR9 is necessary...

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Detalhes bibliográficos
Main Authors: Wuest, Todd, Austin, Bobbie Ann, Uematsu, Satoshi, Thapa, Manoj, Akira, Shizuo, Carr, Daniel J. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1586219/
https://ncbi.nlm.nih.gov/pubmed/16884784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2006.06.020
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