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Intermolecular interactions between dimeric calcium-sensing receptor monomers are important for its normal function

We recently demonstrated that the G protein-coupled, extracellular calcium-sensing receptor (CaR) forms disulfide-linked dimers. The functional significance of dimerization of this receptor was suggested by our earlier observations that CaRs carrying certain point mutations exert dominant negative e...

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Detalhes bibliográficos
Main Authors: Bai, Mei, Trivedi, Sunita, Kifor, Olga, Quinn, Stephen J., Brown, Edward M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15855/
https://ncbi.nlm.nih.gov/pubmed/10077597
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