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Radiolabeling of MAG(3)-morpholino oligomers with (188)Re at high labeling efficiency and specific radioactivity for tumor pretargeting

We are investigating a novel pretargeting approach involving an initial IV injection of antitumor antibody conjugated with a phosphorodiamidate morpholino oligomer (MORF, a DNA analog) and the subsequent IV injection of the radiolabeled complement oligomer (cMORF). In this paper, the cMORF was label...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Guozheng, Dou, Shuping, He, Jiang, Yin, Dongguang, Gupta, Suresh, Zhang, Surong, Wang, Yi, Rusckowski, Mary, Hnatowich, Donald J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1584307/
https://ncbi.nlm.nih.gov/pubmed/16730997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apradiso.2006.04.005
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