Targeting Receptor Tyrosine Kinase on Lymphatic Endothelial Cells for the Therapy of Colon Cancer Lymph Node Metastasis

Oral treatment with the dual-receptor tyrosine kinase inhibitor AEE788 effectively reduces the number of peritumoral lymphatic vessels and the incidence of lymph node metastasis in nude mice with human HT29 colon cancer cells growing in the cecum. Whether inhibition of lymph node metastasis in colon...

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Autores principales: Rebhun, Robert B, Langley, Robert R, Yokoi, Kenji, Fan, Dominic, Gershenwald, Jeffrey E, Fidler, Isaiah J
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press Inc. 2006
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1584298/
https://ncbi.nlm.nih.gov/pubmed/16984732
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