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In vitro suicide inhibition of self-splicing of a group I intron from Pneumocystis carinii by an N3′ → P5′ phosphoramidate hexanucleotide
Binding enhancement by tertiary interactions is a strategy that takes advantage of the higher order folding of functionally important RNAs to bind short nucleic acid-based compounds tightly and more specifically than possible by simple base pairing. For example, tertiary interactions enhance binding...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC15838/ https://ncbi.nlm.nih.gov/pubmed/10077580 |
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