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wasted away, a Drosophila mutation in triosephosphate isomerase, causes paralysis, neurodegeneration, and early death

To identify genes required for maintaining neuronal viability, we screened our collection of Drosophila temperature-sensitive paralytic mutants for those exhibiting shortened lifespan and neurodegeneration. Here, we describe the characterization of wasted away (wstd), a recessive, hypomorphic mutati...

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Détails bibliographiques
Auteurs principaux: Gnerer, Joshua P., Kreber, Robert A., Ganetzky, Barry
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1581428/
https://ncbi.nlm.nih.gov/pubmed/17008404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606887103
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