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Mechanisms by which SCN5A mutation N(1325)S causes cardiac arrhythmias and sudden death in vivo
OBJECTIVE: Mutations in the cardiac sodium channel gene SCN5A are responsible for type-3 long QT disease (LQT3). The genesis of cardiac arrhythmias in LQT3 is multifaceted, and the aim of this study was to further explore mechanisms by which SCN5A mutations lead to arrhythmogenesis in vivo. METHODS:...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1579709/ https://ncbi.nlm.nih.gov/pubmed/14736542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardiores.2003.11.007 |
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