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Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
BACKGROUND: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level probe intensities, then deriving significance by comparing these expression levels between conditions. The proposed PL-LM...
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1579233/ https://ncbi.nlm.nih.gov/pubmed/16934150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-391 |
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