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Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression

BACKGROUND: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level probe intensities, then deriving significance by comparing these expression levels between conditions. The proposed PL-LM...

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Detalhes bibliográficos
Autor principal: Lemieux, Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1579233/
https://ncbi.nlm.nih.gov/pubmed/16934150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-391
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