Trastuzumab in combination with metronomic cyclophosphamide and methotrexate in patients with HER-2 positive metastatic breast cancer

BACKGROUND: HER2/neu overexpression is linked to promotion of angiogenesis in breast cancer. We therefore tested the activity of the combination of Trastuzumab with metronomic, low dose chemotherapy with cyclophosphamide (CTX) and methotrexate (MTX) in metastatic breast cancer (MBC). METHODS: Betwee...

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Hlavní autoři: Orlando, Laura, Cardillo, Anna, Ghisini, Raffaella, Rocca, Andrea, Balduzzi, Alessandra, Torrisi, Rosalba, Peruzzotti, Giulia, Goldhirsch, Aron, Pietri, Elisabetta, Colleoni, Marco
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2006
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1579231/
https://ncbi.nlm.nih.gov/pubmed/16978400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-225
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