Trastuzumab in combination with metronomic cyclophosphamide and methotrexate in patients with HER-2 positive metastatic breast cancer

BACKGROUND: HER2/neu overexpression is linked to promotion of angiogenesis in breast cancer. We therefore tested the activity of the combination of Trastuzumab with metronomic, low dose chemotherapy with cyclophosphamide (CTX) and methotrexate (MTX) in metastatic breast cancer (MBC). METHODS: Betwee...

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Detalhes bibliográficos
Main Authors: Orlando, Laura, Cardillo, Anna, Ghisini, Raffaella, Rocca, Andrea, Balduzzi, Alessandra, Torrisi, Rosalba, Peruzzotti, Giulia, Goldhirsch, Aron, Pietri, Elisabetta, Colleoni, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1579231/
https://ncbi.nlm.nih.gov/pubmed/16978400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-225
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