Trastuzumab in combination with metronomic cyclophosphamide and methotrexate in patients with HER-2 positive metastatic breast cancer

BACKGROUND: HER2/neu overexpression is linked to promotion of angiogenesis in breast cancer. We therefore tested the activity of the combination of Trastuzumab with metronomic, low dose chemotherapy with cyclophosphamide (CTX) and methotrexate (MTX) in metastatic breast cancer (MBC). METHODS: Betwee...

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Главные авторы: Orlando, Laura, Cardillo, Anna, Ghisini, Raffaella, Rocca, Andrea, Balduzzi, Alessandra, Torrisi, Rosalba, Peruzzotti, Giulia, Goldhirsch, Aron, Pietri, Elisabetta, Colleoni, Marco
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2006
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1579231/
https://ncbi.nlm.nih.gov/pubmed/16978400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-225
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