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The effect of high dosage of methotrexate, associated with folinic acid, on the suppression of tuberculin sensitivity in guinea-pigs

Methotrexate administered over a period of 8 weeks reduced tuberculin skin sensitivity in guinea-pigs, the effect waning in the later part of the period. The delayed administration of folinic acid successfully reduced the toxicity of methotrexate so that the dose of the latter could be increased thr...

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Detalhes bibliográficos
Main Authors: Hart, P. D'Arcy, Rees, R. J. W., Niven, Janet S. F.
Formato: Artigo
Idioma:Inglês
Publicado em: 1968
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578891/
https://ncbi.nlm.nih.gov/pubmed/5300374
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