VSIG4, a B7 family–related protein, is a negative regulator of T cell activation

T cell activation by APCs is positively and negatively regulated by members of the B7 family. We have identified a previously unknown function for B7 family–related protein V-set and Ig domain–containing 4 (VSIG4). In vitro experiments using VSIG4-Ig fusion molecules showed that VSIG4 is a strong ne...

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Detalhes bibliográficos
Main Authors: Vogt, Lorenz, Schmitz, Nicole, Kurrer, Michael O., Bauer, Monika, Hinton, Heather I., Behnke, Silvia, Gatto, Dominique, Sebbel, Peter, Beerli, Roger R., Sonderegger, Ivo, Kopf, Manfred, Saudan, Philippe, Bachmann, Martin F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578631/
https://ncbi.nlm.nih.gov/pubmed/17016562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25673
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