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Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity

Menkes disease, a fatal neurodegenerative disorder resulting in seizures, hypotonia, and failure to thrive, is due to inherited loss-of-function mutations in the gene encoding a copper-transporting ATPase (Atp7a) on the X chromosome. Although affected patients exhibit signs and symptoms of copper de...

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Bibliografiset tiedot
Päätekijät: Schlief, Michelle L., West, Tim, Craig, Ann Marie, Holtzman, David M., Gitlin, Jonathan D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2006
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578502/
https://ncbi.nlm.nih.gov/pubmed/17003121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605390103
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