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Ability of isoprinosine to restore interleukin-2 production and T cell proliferation in autoimmune mice.

Autoimmune mice bearing the single autosomal recessive gene 1pr are unable to produce the T cell growth factor, interleukin-2 (IL-2). A physiological consequence of this defect is the inability of T cells from C57B1/6J-lpr/lpr mice to respond to antigen presented by macrophages. In an attempt to rev...

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Detalhes bibliográficos
Main Authors: Fischbach, M, Talal, N
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1577290/
https://ncbi.nlm.nih.gov/pubmed/2412742
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