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Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation

Some mammalian species show an ability to discriminate between different lipopolysaccharide (LPS) partial structures (for example, lipid A and its congener LA-14-PP, which lacks secondary acyl chains), whereas others do not. Using a novel genetic complementation system involving the transduction of...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Poltorak, A., Ricciardi-Castagnoli, P., Citterio, S., Beutler, B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15771/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10681462/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.040565397
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