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Selective depression of thymus-independent anti-DNP antibody responses induced by adult but not neonatal splenectomy.

The effect of splenectomy was assessed on rats' capacity to respond to 2,4-dinitrophenol (DNP) conjugated to spider crab haemocyanin (MSH) or hydroxyethyl starch (HES). The response to DNP-HES was profoundly suppressed in all immunoglobulin classes and subclasses by adult splenectomy. This loss...

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Detalhes bibliográficos
Main Authors: Gray, D, Chassoux, D, MacLennan, I C, Bazin, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576989/
https://ncbi.nlm.nih.gov/pubmed/2408798
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