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Overexpression of heat shock protein 70 restores the structural stability and functional defects of temperature-sensitive mutant of large T antigen at nonpermissive temperature

The effects of heat shock protein 70 (Hsp70), a molecular chaperone, on the degradation and functional alterations of a mutant large T antigen induced by a nonpermissive temperature were examined. In this study, mouse tracheal epithelial TM02-3 cells harboring temperature-sensitive simian virus 40 l...

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Detalhes bibliográficos
Main Authors: Tabuchi, Yoshiaki, Kuribayashi, Ryosuke, Takasaki, Ichiro, Doi, Takeshi, Sakai, Hideki, Takeguchi, Noriaki, Kondo, Takashi, Ohtsuka, Kenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Stress Society International 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576476/
https://ncbi.nlm.nih.gov/pubmed/17009599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1379/CSC-193R.1
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