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Exogenous heat shock protein 70 mediates sepsis manifestations and decreases the mortality rate in rats

Mammalian responses to bacterial lipopolysaccharide (LPS) from the outer membrane of Gram-negative bacteria can lead to an uncontrolled inflammatory reaction that can be deadly for the host. We checked whether heat shock protein 70 (Hsp70) protein is able to protect animals from the deleterious effe...

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Autori principali: Kustanova, Gul'sara A., Murashev, Arcady N., Karpov, Vadim L., Margulis, Boris A., Guzhova, Irina V., Prokhorenko, Izabella R., Grachev, Sergei V., Evgen'ev, Michael B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Stress Society International 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576474/
https://ncbi.nlm.nih.gov/pubmed/17009601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1379/CSC-195R.1
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