Rosiglitazone ameliorates abnormal expression and activity of protein tyrosine phosphatase 1B in the skeletal muscle of fat-fed, streptozotocin-treated diabetic rats

1. Protein tyrosine phosphatase 1B (PTP1B) acts as a physiological negative regulator of insulin signaling by dephosphorylating the activated insulin receptor (IR). Here we examine the role of PTP1B in the insulin-sensitizing action of rosiglitazone (RSG) in skeletal muscle and liver. 2. Fat-fed, st...

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Detalhes bibliográficos
Principais autores: Wu, Yong, Ouyang, Jing Ping, Wu, Ke, Wang, Shi Shun, Wen, Chong Yuan, Xia, Zheng Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576260/
https://ncbi.nlm.nih.gov/pubmed/15997237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706306
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