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Potential of ketamine and midazolam, individually or in combination, to induce apoptotic neurodegeneration in the infant mouse brain

1. Recently, it was reported that anesthetizing infant rats for 6 h with a combination of anesthetic drugs (midazolam, nitrous oxide, isoflurane) caused widespread apoptotic neurodegeneration in the developing brain, followed by lifelong cognitive deficits. It has also been reported that ketamine tr...

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Detalhes bibliográficos
Main Authors: Young, Chainllie, Jevtovic-Todorovic, Vesna, Qin, Yue-Qin, Tenkova, Tatyana, Wang, Haihui, Labruyere, Joann, Olney, John W
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576258/
https://ncbi.nlm.nih.gov/pubmed/15997239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706301
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