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Opioid tolerance in periaqueductal gray neurons isolated from mice chronically treated with morphine

1. The midbrain periaqueductal gray (PAG) is a major site of opioid analgesic action, and a significant site of cellular adaptations to chronic morphine treatment (CMT). We examined μ-opioid receptor (MOP) regulation of voltage-gated calcium channel currents (I(Ca)) and G-protein-activated K channel...

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Bibliographic Details
Main Authors: Bagley, Elena E, Chieng, Billy C H, Christie, MacDonald J, Connor, Mark
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576256/
https://ncbi.nlm.nih.gov/pubmed/15980868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706315
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