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Somatostatin at nanomolar concentration reduces collagen I and III synthesis by, but not proliferation of activated rat hepatic stellate cells

1. Previous studies have shown antifibrotic effects of somatostatin. Since hepatic stellate cells (HSC) express somatostatin receptors and play a key role in hepatic fibrogenesis, we investigated the in vitro antifibrotic effect of somatostatin on rat HSC. 2. At day 12 after isolation, cells were ex...

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Autors principals: Reynaert, Hendrik, Rombouts, Krista, Jia, Yutao, Urbain, Daniel, Chatterjee, Nirjhar, Uyama, Naoki, Geerts, Albert
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576247/
https://ncbi.nlm.nih.gov/pubmed/15980876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706298
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