Inhibition of the antigen-induced activation of rodent mast cells by putative Janus kinase 3 inhibitors WHI-P131 and WHI-P154 in a Janus kinase 3-independent manner

1. We analyzed the effects of the Janus kinase 3 (Jak3)-specific inhibitor WHI-P131 (4-(4′-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline) and the Jak3/Syk inhibitor WHI-P154 (4-(3′-bromo-4′-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline) on the antigen-induced activation of mast cells. 2. In the rat...

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Hlavní autoři: Linwong, Watchara, Hirasawa, Noriyasu, Aoyama, Suzue, Hamada, Hirofumi, Saito, Takashi, Ohuchi, Kazuo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576194/
https://ncbi.nlm.nih.gov/pubmed/15852029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706240
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