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The mechanism underlying the contractile effect of a chemotactic peptide, formyl-Met-Leu-Phe on the guinea-pig Taenia coli

1. The contractile mechanism of N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP) was investigated in the guinea-pig Taenia coli, by simultaneously monitoring the changes in the cytosolic Ca(2+) concentration ([Ca(2+)](i)) and force. 2. fMLP induced a significant elevation of [Ca(2+)](i) and forc...

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Detalhes bibliográficos
Main Authors: Kawata, Hiroshi, Hirano, Katsuya, Nishimura, Junji, Kubo, Chiharu, Kanaide, Hideo
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576144/
https://ncbi.nlm.nih.gov/pubmed/15735654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706181
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