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Effects of synaptotagmin reveal two distinct mechanisms of agonist-stimulated internalization of the M4 muscarinic acetylcholine receptor

1. Synaptotagmin has been reported to function in clathrin-mediated endocytosis. Here, we investigated its involvement in agonist-stimulated internalization of M4 muscarinic acetylcholine receptors exogenously expressed in human embryonic kidney (HEK-293 tsA201) cells. 2. Synaptotagmin I was present...

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Hlavní autoři: Madziva, Michael T, Bai, Jihong, Bhalla, Akhil, Chapman, Edwin R, Edwardson, J Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576056/
https://ncbi.nlm.nih.gov/pubmed/15778699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706035
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