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Studies using isolated uterine and other preparations show bimatoprost and prostanoid FP agonists have different activity profiles
1. The pharmacology of bimatoprost, a synthetic prostaglandin-amide, was examined in prostaglandin F(2α) (PGF(2α))-sensitive preparations. Bimatoprost potently contracted the rabbit isolated uterus (pEC(50)=7.92±0.16). In contrast, bimatoprost exhibited weak excitatory activity in human myometrium f...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576027/ https://ncbi.nlm.nih.gov/pubmed/15678094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706044 |
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