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Dextromethorphan differentially affects opioid antinociception in rats

1. Opioid drugs such as morphine and meperidine are widely used in clinical pain management, although they can cause some adverse effects. A number of studies indicate that N-methyl-D-aspartate (NMDA) receptors may play a role in the mechanism of morphine analgesia, tolerance and dependence. Being a...

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Autors principals: Chen, Shiou-Lan, Huang, Eagle Yi-Kung, Chow, Lok-Hi, Tao, Pao-Luh
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576017/
https://ncbi.nlm.nih.gov/pubmed/15655510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706086
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