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Prediction of the risk of Torsade de Pointes using the model of isolated canine Purkinje fibres
1. Torsade de Pointes (TdP) is a well-described major risk associated with various kinds of drugs. However, prediction of this risk is still uncertain both in preclinical and clinical trials. We tested 45 reference compounds on the model of isolated canine Purkinje fibres. Of them, 22 are clearly as...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576014/ https://ncbi.nlm.nih.gov/pubmed/15655517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706070 |
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