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Positron emission tomography using (18)F-labelled endothelin-1 reveals prevention of binding to cardiac receptors owing to tissue-specific clearance by ET(B) receptors in vivo
1. Our aim was to synthesise an (18)F analogue of endothelin-1 (ET-1), to dynamically image ET receptors in vivo by positron emission tomography (PET) and to elucidate the function of the ET(B) subtype as a clearing receptor in organs expressing high densities including kidney and lung. 2. [(18)F]-E...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1575985/ https://ncbi.nlm.nih.gov/pubmed/15644875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706064 |
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