Identification of R(−)-isomer of efonidipine as a selective blocker of T-type Ca(2+) channels

1. Efonidipine, a derivative of dihydropyridine Ca(2+) antagonist, is known to block both L- and T-type Ca(2+) channels. It remains to be clarified, however, whether efonidipine affects other voltage-dependent Ca(2+) channel subtypes such as N-, P/Q- and R-types, and whether the optical isomers of e...

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Bibliografske podrobnosti
Main Authors: Furukawa, Taiji, Miura, Reiko, Honda, Mitsuyoshi, Kamiya, Natsuko, Mori, Yasuo, Takeshita, Satoshi, Isshiki, Takaaki, Nukada, Toshihide
Format: Artigo
Jezik:Inglês
Izdano: 2004
Teme:
Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575949/
https://ncbi.nlm.nih.gov/pubmed/15545287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705944
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