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Sphingosine 1-phosphate-induced vasoconstriction is elevated in mesenteric resistance arteries from aged female rats

1. Sphingosine 1-phosphate (S1P), a bioactive lipid, signals through cell surface receptors to induce vasoconstriction and activate endothelial nitric oxide synthase (eNOS), suggesting a role for S1P in vascular tone modulation. 2. Using a model of aging in female rats, we investigated the vasoactiv...

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Detalhes bibliográficos
Main Authors: Hemmings, D G, Xu, Y, Davidge, S T
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575332/
https://ncbi.nlm.nih.gov/pubmed/15326035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705752
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