Lipoxins and novel 15-epi-lipoxin analogs display potent anti-inflammatory actions after oral administration

1. Lipoxins (LX) and aspirin-triggered 15-epi-lipoxins (ATL) exert potent anti-inflammatory actions. In the present study, we determined the anti-inflammatory efficacy of endogenous LXA(4) and LXB(4), the stable ATL analog ATLa2, and a series of novel 3-oxa-ATL analogs (ZK-996, ZK-990, ZK-994, and Z...

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Detalhes bibliográficos
Main Authors: Bannenberg, Gerard, Moussignac, Rose-Laure, Gronert, Karsten, Devchand, Pallavi R, Schmidt, Birgitta A, Guilford, William J, Bauman, John G, Subramanyam, Babu, Daniel Perez, H, Parkinson, John F, Serhan, Charles N
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575273/
https://ncbi.nlm.nih.gov/pubmed/15302682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705912
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