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Increased wakefulness, motor activity and decreased theta activity after blockade of the 5-HT(2B) receptor by the subtype-selective antagonist SB-215505

1. Serotonin-2 receptor antagonists, like ritanserin, greatly enhance deep slow wave sleep (SWS-2) and low-frequency EEG power in humans and rodents. 5-HT(2A) and 5-HT(2C) receptors may be involved in these effects, but the role of the 5-HT(2B) receptor is still unclear. 2. To investigate the role o...

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Detalhes bibliográficos
Main Authors: Kantor, Sandor, Jakus, Rita, Balogh, Brigitta, Benko, Anita, Bagdy, Gyorgy
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575194/
https://ncbi.nlm.nih.gov/pubmed/15265808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705887
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