Antianxiety and antidepressant-like effects of AC-5216, a novel mitochondrial benzodiazepine receptor ligand

1. We investigated the ability of N-benzyl-N-ethyl-2-(7,8-dihydro-7-methyl-8-oxo-2-phenyl-9H-purin-9-yl)acetamide (AC-5216), a novel mitochondrial benzodiazepine receptor (MBR) ligand, to produce anti-anxiety and antidepressant-like effects in various animal models. 2. AC-5216 showed high affinity f...

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Detalhes bibliográficos
Main Authors: Kita, Atsuko, Kohayakawa, Hitoshi, Kinoshita, Tomoko, Ochi, Yoshiaki, Nakamichi, Keiko, Kurumiya, Satoshi, Furukawa, Kiyoshi, Oka, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575165/
https://ncbi.nlm.nih.gov/pubmed/15249420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705681
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