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Prostacyclin release and receptor activation: differential control of human pulmonary venous and arterial tone

1. In human pulmonary vascular preparations, precontracted arteries were more sensitive to the relaxant effect of acetylcholine (ACh) than veins (pD(2) values: 7.25±0.08 (n=23) and 5.92±0.09 (n=25), respectively). Therefore, the role of prostacyclin (PGI(2)) was explored to examine whether this medi...

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Autors principals: Norel, Xavier, Walch, Laurence, Gascard, Jean-Pierre, Montpreville, Vincent de, Brink, Charles
Format: Artigo
Idioma:Inglês
Publicat: 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575053/
https://ncbi.nlm.nih.gov/pubmed/15172959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705843
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